Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome

PURPOSE: To investigate how necroptosisis, i.e. programmed necrosis, is involved in MODS, and to examine whether Nec-1, a specific necroptosis inhibitor, ameliorates multiorgan injury in MODS. EXPERIMENTAL DESIGN: A model of MODS was established in six-week old SD rats using fracture trauma followed...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cui, Yao-Li, Qiu, Li-Hua, Zhou, Shi-Yong, Li, Lan-Fang, Qian, Zheng-Zi, Liu, Xian-Ming, Zhang, Hui-Lai, Ren, Xiu-Bao, Wang, Yong-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593618/
https://ncbi.nlm.nih.gov/pubmed/28915647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18252
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