HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance

Heat shock protein 90 (HSP90) stabilizes numerous oncoproteins and, therefore, its inhibition has emerged as a promising antineoplastic strategy for diverse malignancies. In this study, we determined the therapeutic effects and mechanisms of action of a specific HSP90 inhibitor, 17-dimethylamino-eth...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Kim, Jeong Goo, Lee, Sang Chul, Kim, Ok-Hee, Kim, Kee-Hwan, Song, Kyo Young, Lee, Sang Kuon, Choi, Byung Jo, Jeong, Wonjun, Kim, Say-June
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593576/
https://ncbi.nlm.nih.gov/pubmed/28915605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17007
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