Eugenol alleviated breast precancerous lesions through HER2/PI3K-AKT pathway-induced cell apoptosis and S-phase arrest

Eugenol can be separated from the oil extract of clove bud, and has many pharmacological functions such as anticancer and transdermal absorption. HER2/PI3K-AKT is a key signaling pathway in the development of breast cancer. In this study, 80 μM eugenol could significantly inhibit the proliferation o...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Ma, Min, Ma, Yi, Zhang, Gui-Juan, Liao, Rui, Jiang, Xue-Feng, Yan, Xian-Xin, Bie, Feng-Jie, Li, Xiao-Bo, Lv, Yan-Hong
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593562/
https://ncbi.nlm.nih.gov/pubmed/28915591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17626
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