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Attenuation of dopamine-modulated prefrontal value signals underlies probabilistic reward learning deficits in old age

Probabilistic reward learning is characterised by individual differences that become acute in aging. This may be due to age-related dopamine (DA) decline affecting neural processing in striatum, prefrontal cortex, or both. We examined this by administering a probabilistic reward learning task to you...

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Veröffentlicht in:eLife
Hauptverfasser: de Boer, Lieke, Axelsson, Jan, Riklund, Katrine, Nyberg, Lars, Dayan, Peter, Bäckman, Lars, Guitart-Masip, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593512/
https://ncbi.nlm.nih.gov/pubmed/28870286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26424
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