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Attenuation of dopamine-modulated prefrontal value signals underlies probabilistic reward learning deficits in old age

Probabilistic reward learning is characterised by individual differences that become acute in aging. This may be due to age-related dopamine (DA) decline affecting neural processing in striatum, prefrontal cortex, or both. We examined this by administering a probabilistic reward learning task to you...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: de Boer, Lieke, Axelsson, Jan, Riklund, Katrine, Nyberg, Lars, Dayan, Peter, Bäckman, Lars, Guitart-Masip, Marc
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593512/
https://ncbi.nlm.nih.gov/pubmed/28870286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26424
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