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Advanced glycation end products decrease collagen I levels in fibroblasts from the vaginal wall of patients with POP via the RAGE, MAPK and NF-κB pathways

The present study was carried out to observe the impact of advanced glycation end products (AGEs) on collagen I derived from vaginal fibroblasts in the context of pelvic organ prolapse (POP), and explore the downstream effects on MAPK and nuclear factor-κB (NF-κB) signaling. After treating primary c...

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Publicat a:Int J Mol Med
Autors principals: Chen, Yi-Song, Wang, Xiao-Juan, Feng, Weiwei, Hua, Ke-Qin
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593496/
https://ncbi.nlm.nih.gov/pubmed/28849117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3097
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