Intra‐Target Microdosing – A Novel Drug Development Approach: Proof of Concept, Safety, and Feasibility Study in Humans

Intra‐Target Microdosing (ITM) is a novel drug development approach aimed at increasing the efficiency of first‐in‐human (FIH) testing of new molecular entities (NMEs). ITM combines intra‐target drug delivery and “microdosing,” the subpharmacological systemic exposure. We hypothesized that when the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Transl Sci
Main Authors: Burt, T, MacLeod, D, Lee, K, Santoro, A, DeMasi, DK, Hawk, T, Feinglos, M, Rowland, M, Noveck, RJ
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593161/
https://ncbi.nlm.nih.gov/pubmed/28689370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12477
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker