Exceptional durable response to everolimus in a patient with biphenotypic breast cancer harboring an STK11 variant

Metastatic triple-negative breast cancer comprises 12%–17% of breast cancers and carries a poor prognosis relative to other breast cancer subtypes. Treatment options in this disease are largely limited to systemic chemotherapy. A majority of clinical studies assessing efficacy of targeted therapeuti...

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Veröffentlicht in:Cold Spring Harb Mol Case Stud
Hauptverfasser: Parachoniak, Christine A., Rankin, Andrew, Gaffney, Bernadette, Hartmaier, Ryan, Spritz, Dan, Erlich, Rachel L., Miller, Vincent A., Morosini, Deborah, Stephens, Phil, Ross, Jeffrey S., Keech, John, Chmielecki, Juliann
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2017
Schlagworte:
Research Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593157/
https://ncbi.nlm.nih.gov/pubmed/28550065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a000778
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