Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

Recent genome-wide association studies (GWAS) have identified variants associated with high-density lipoprotein cholesterol (HDL-C) located in or near the ANGPTL8 gene. Given the extensive sharing of GWAS loci across populations, we hypothesized that at least one shared variant at this locus affects...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Cannon, Maren E., Duan, Qing, Wu, Ying, Zeynalzadeh, Monica, Xu, Zheng, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Civelek, Mete, Lusis, Aldons J., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Tang, Hua, Laakso, Markku, Li, Yun, Mohlke, Karen L.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2017
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592946/
https://ncbi.nlm.nih.gov/pubmed/28754724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300088
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