Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol

Genome-wide association studies (GWASs) have identified more than 150 loci associated with blood lipid and cholesterol levels; however, the functional and molecular mechanisms for many associations are unknown. We examined the functional regulatory effects of candidate variants at the GALNT2 locus a...

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Publicado no:Am J Hum Genet
Main Authors: Roman, Tamara S., Marvelle, Amanda F., Fogarty, Marie P., Vadlamudi, Swarooparani, Gonzalez, Arlene J., Buchkovich, Martin L., Huyghe, Jeroen R., Fuchsberger, Christian, Jackson, Anne U., Wu, Ying, Civelek, Mete, Lusis, Aldons J., Gaulton, Kyle J., Sethupathy, Praveen, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Boehnke, Michael, Mohlke, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678431/
https://ncbi.nlm.nih.gov/pubmed/26637976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.10.016
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