PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but conception can occur in its absence

Activation of the egg by the sperm is the first, vital stage of embryogenesis. The sperm protein PLCζ has been proposed as the physiological agent that triggers the Ca(2+) oscillations that normally initiate embryogenesis. Consistent with this, recombinant PLCζ induces Ca(2+) oscillations in eggs an...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Hachem, Alaa, Godwin, Jonathan, Ruas, Margarida, Lee, Hoi Chang, Ferrer Buitrago, Minerva, Ardestani, Goli, Bassett, Andrew, Fox, Sebastian, Navarrete, Felipe, de Sutter, Petra, Heindryckx, Björn, Fissore, Rafael, Parrington, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592814/
https://ncbi.nlm.nih.gov/pubmed/28694258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.150227
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