A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility

BACKGROUND: Male factor and idiopathic infertility contribute significantly to global infertility, with abnormal testicular gene expression considered to be a major cause. Certain types of male infertility are caused by failure of the sperm to activate the oocyte, a process normally regulated by cal...

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Main Authors: Kashir, Junaid, Konstantinidis, Michalis, Jones, Celine, Lemmon, Bernadette, Chang Lee, Hoi, Hamer, Rebecca, Heindryckx, Bjorn, Deane, Charlotte M., De Sutter, Petra, Fissore, Rafael A., Parrington, John, Wells, Dagan, Coward, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241606/
https://ncbi.nlm.nih.gov/pubmed/22095789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/der384
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