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PHASE I TRIAL OF A BIVALENT GANGLIOSIDES VACCINE IN COMBINATION WITH β-GLUCAN: FOR HIGH-RISK NEUROBLASTOMA IN SECOND OR LATER REMISSION

BACKGROUND: To report on a phase I trial designed to find the maximally tolerated dose in children of the immunological adjuvant OPT-821 in a vaccine containing neuroblastoma-associated antigens (GD2 and GD3) (Clinicaltrials.gov NCT00911560). Secondary objectives were to obtain preliminary data on i...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Kushner, Brian H., Cheung, Irene Y., Modak, Shakeel, Kramer, Kim, Ragupathi, Govind, Cheung, Nai-Kong V.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592799/
https://ncbi.nlm.nih.gov/pubmed/24520094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1012
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