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The HIV-1 repeated sequence R as a robust hot-spot for copy-choice recombination

Template switching during reverse transcription is crucial for retroviral replication. While strand transfer on the terminal repeated sequence R is essential to achieve reverse transcription, template switching from internal regions of the genome (copy choice) leads to genetic recombination. We have...

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Detalhes bibliográficos
Main Authors: Moumen, Abdeladim, Polomack, Lucette, Roques, Bernard, Buc, Henri, Negroni, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55921/
https://ncbi.nlm.nih.gov/pubmed/11557813
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