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Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility

Homing endonucleases confer mobility to their host intervening sequence, either an intron or intein, by catalyzing a highly specific double-strand break in a cognate allele lacking the intervening sequence. These proteins are characterized by their ability to bind long DNA target sites (14–40 bp) an...

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Bibliografische gegevens
Hoofdauteurs: Chevalier, Brett S., Stoddard, Barry L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55915/
https://ncbi.nlm.nih.gov/pubmed/11557808
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