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Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility

Homing endonucleases confer mobility to their host intervening sequence, either an intron or intein, by catalyzing a highly specific double-strand break in a cognate allele lacking the intervening sequence. These proteins are characterized by their ability to bind long DNA target sites (14–40 bp) an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chevalier, Brett S., Stoddard, Barry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55915/
https://ncbi.nlm.nih.gov/pubmed/11557808
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