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Asymmetric synthesis of γ-lactones through Koga amine-controlled addition of enediolates to α,β-unsaturated sulfoxonium salts

A chiral Koga amine-controlled asymmetric synthesis of cis-γ-lactones through a formal [3 + 2] cycloaddition of enediolates with α,β-unsaturated sulfoxonium salts is described. The desired structural motif was formed in moderate to good yields (50–71% for 13 examples), with good to very good diaster...

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Bibliografske podrobnosti
izdano v:J Org Chem
Main Authors: Peraino, Nicholas J., Kaster, Sven H., Wheeler, Kraig A., Kerrigan, Nessan J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591458/
https://ncbi.nlm.nih.gov/pubmed/27933807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b02622
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