Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe(3)O(4) nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have restricted its chemotherapeutic potential. To overcome these restrictions, CPT was encapsulated in CEF (cyclodextrin-EDTA-FE(3)O(4)), a composi...

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Publicado no:Sci Rep
Main Authors: Krishnan, Poorani, Rajan, Mariappan, Kumari, Sharmilah, Sakinah, S., Priya, Sivan Padma, Amira, Fatin, Danjuma, Lawal, Pooi Ling, Mok, Fakurazi, Sharida, Arulselvan, Palanisamy, Higuchi, Akon, Arumugam, Ramitha, Alarfaj, Abdullah A., Munusamy, Murugan A., Hamat, Rukman Awang, Benelli, Giovanni, Murugan, Kadarkarai, Kumar, S. Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591276/
https://ncbi.nlm.nih.gov/pubmed/28887536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09140-1
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