Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe(3)O(4) nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have restricted its chemotherapeutic potential. To overcome these restrictions, CPT was encapsulated in CEF (cyclodextrin-EDTA-FE(3)O(4)), a composi...

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Pubblicato in:Sci Rep
Autori principali: Krishnan, Poorani, Rajan, Mariappan, Kumari, Sharmilah, Sakinah, S., Priya, Sivan Padma, Amira, Fatin, Danjuma, Lawal, Pooi Ling, Mok, Fakurazi, Sharida, Arulselvan, Palanisamy, Higuchi, Akon, Arumugam, Ramitha, Alarfaj, Abdullah A., Munusamy, Murugan A., Hamat, Rukman Awang, Benelli, Giovanni, Murugan, Kadarkarai, Kumar, S. Suresh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591276/
https://ncbi.nlm.nih.gov/pubmed/28887536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09140-1
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