Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe(3)O(4) nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have restricted its chemotherapeutic potential. To overcome these restrictions, CPT was encapsulated in CEF (cyclodextrin-EDTA-FE(3)O(4)), a composi...

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Publicat a:Sci Rep
Autors principals: Krishnan, Poorani, Rajan, Mariappan, Kumari, Sharmilah, Sakinah, S., Priya, Sivan Padma, Amira, Fatin, Danjuma, Lawal, Pooi Ling, Mok, Fakurazi, Sharida, Arulselvan, Palanisamy, Higuchi, Akon, Arumugam, Ramitha, Alarfaj, Abdullah A., Munusamy, Murugan A., Hamat, Rukman Awang, Benelli, Giovanni, Murugan, Kadarkarai, Kumar, S. Suresh
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591276/
https://ncbi.nlm.nih.gov/pubmed/28887536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09140-1
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