Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor–Modified T Cells After Failure of Ibrutinib

PURPOSE: We evaluated the safety and feasibility of anti-CD19 chimeric antigen receptor–modified T (CAR-T) cell therapy in patients with chronic lymphocytic leukemia (CLL) who had previously received ibrutinib. METHODS: Twenty-four patients with CLL received lymphodepleting chemotherapy and anti-CD1...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Oncol
Prif Awduron: Turtle, Cameron J., Hay, Kevin A., Hanafi, Laïla-Aïcha, Li, Daniel, Cherian, Sindhu, Chen, Xueyan, Wood, Brent, Lozanski, Arletta, Byrd, John C., Heimfeld, Shelly, Riddell, Stanley R., Maloney, David G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Clinical Oncology 2017
Pynciau:
ORIGINAL REPORTS
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590803/
https://ncbi.nlm.nih.gov/pubmed/28715249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.72.8519
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