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Dynamic equilibrium of lung T(rm) dictates waning immunity after Influenza A infection

Lung resident memory (T(rm)) CD8 T cells induced by influenza A virus (IAV) are pivotal for providing heterosubtypic immunity, but are not maintained long term, causing gradual loss of protection. This contrasts sharply with long-term maintenance of T(rm) induced by localized infections of the skin...

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Vydáno v:Sci Immunol
Hlavní autoři: Slütter, Bram, Van Braeckel-Budimir, Natalija, Abboud, Georges, Varga, Steven M., Salek-Ardakani, Shahram, Harty, John T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590757/
https://ncbi.nlm.nih.gov/pubmed/28783666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aag2031
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