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A heterochromatin-dependent transcription machinery drives piRNA expression

Nuclear small RNA pathways safeguard genome integrity by establishing transcription-repressing heterochromatin at transposable elements. This inevitably also targets the transposon-rich source loci of the small RNAs themselves. How small RNA source loci are efficiently transcribed while transposon p...

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Publicat a:Nature
Autors principals: Andersen, Peter Refsing, Tirian, Laszlo, Vunjak, Milica, Brennecke, Julius
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590728/
https://ncbi.nlm.nih.gov/pubmed/28847004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23482
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