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Molecular heterogeneity at the network level: high-dimensional testing, clustering and a TCGA case study

MOTIVATION: Molecular pathways and networks play a key role in basic and disease biology. An emerging notion is that networks encoding patterns of molecular interplay may themselves differ between contexts, such as cell type, tissue or disease (sub)type. However, while statistical testing of differe...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Städler, Nicolas, Dondelinger, Frank, Hill, Steven M, Akbani, Rehan, Lu, Yiling, Mills, Gordon B, Mukherjee, Sach
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590725/
https://ncbi.nlm.nih.gov/pubmed/28535188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx322
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