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Molecular heterogeneity at the network level: high-dimensional testing, clustering and a TCGA case study

MOTIVATION: Molecular pathways and networks play a key role in basic and disease biology. An emerging notion is that networks encoding patterns of molecular interplay may themselves differ between contexts, such as cell type, tissue or disease (sub)type. However, while statistical testing of differe...

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Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Städler, Nicolas, Dondelinger, Frank, Hill, Steven M, Akbani, Rehan, Lu, Yiling, Mills, Gordon B, Mukherjee, Sach
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590725/
https://ncbi.nlm.nih.gov/pubmed/28535188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx322
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