Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers

Tafenoquine is an 8-aminoquinoline under investigation for the prevention of relapse in Plasmodium vivax malaria. This open-label, dose-escalation study assessed quantitatively the hemolytic risk with tafenoquine in female healthy volunteers heterozygous for the Mahidol(487A) glucose-6-phosphate deh...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Trop Med Hyg
मुख्य लेखकों: Rueangweerayut, Ronnatrai, Bancone, Germana, Harrell, Emma J., Beelen, Andrew P., Kongpatanakul, Supornchai, Möhrle, Jörg J., Rousell, Vicki, Mohamed, Khadeeja, Qureshi, Ammar, Narayan, Sushma, Yubon, Nushara, Miller, Ann, Nosten, François H., Luzzatto, Lucio, Duparc, Stephan, Kleim, Jörg-Peter, Green, Justin A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society of Tropical Medicine and Hygiene 2017
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590573/
https://ncbi.nlm.nih.gov/pubmed/28749773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.16-0779
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