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Lagrangian Trajectories to Predict the Formation of Population Heterogeneity in Large-Scale Bioreactors

Successful scale-up of bioprocesses requires that laboratory-scale performance is equally achieved during large-scale production to meet economic constraints. In industry, heuristic approaches are often applied, making use of physical scale-up criteria that do not consider cellular needs or properti...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Kuschel, Maike, Siebler, Flora, Takors, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590480/
https://ncbi.nlm.nih.gov/pubmed/28952507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering4020027
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