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Repetitive Short-Term Stimuli Imposed in Poor Mixing Zones Induce Long-Term Adaptation of E. coli Cultures in Large-Scale Bioreactors: Experimental Evidence and Mathematical Model

Rapidly changing concentrations of substrates frequently occur during large-scale microbial cultivations. These changing conditions, caused by large mixing times, result in a heterogeneous population distribution. Here, we present a powerful and efficient modeling approach to predict the influence o...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Nieß, Alexander, Löffler, Michael, Simen, Joana D., Takors, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487534/
https://ncbi.nlm.nih.gov/pubmed/28702020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01195
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