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Is cytotoxicity a determinant of the different in vitro and in vivo effects of bioactives?

BACKGROUND: Foodstuffs of both plant and animal origin contain a wide range of bioactive compounds. Although human intervention studies are mandatory to assess the health effects of bioactives, the in vitro approach is often used to select the most promising molecules to be studied in vivo. To avoid...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Di Nunzio, Mattia, Valli, Veronica, Tomás-Cobos, Lidia, Tomás-Chisbert, Teresa, Murgui-Bosch, Lucía, Danesi, Francesca, Bordoni, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590171/
https://ncbi.nlm.nih.gov/pubmed/28882181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-017-1962-2
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