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Transcription factor EB is involved in autophagy-mediated chemoresistance to doxorubicin in human cancer cells

Transcription factor EB (TFEB) is a master regulator of autophagy activity and lysosomal biogenesis, but its role in autophagy-mediated cell survival and chemotherapy resistance is not completely understood. In this study, we explored whether TFEB played an important role in autophagy-mediated chemo...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Fang, Li-mei, Li, Bin, Guan, Jun-jie, Xu, Hai-dong, Shen, Gen-hai, Gao, Quan-gen, Qin, Zheng-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589965/
https://ncbi.nlm.nih.gov/pubmed/28603284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.25
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