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Deamination-independent restriction of LINE-1 retrotransposition by APOBEC3H

The APOBEC3 family of cytosine deaminase enzymes are able to restrict replication of retroelements, such as LINE-1. However, each of the seven APOBEC3 enzymes have been reported to act differentially to prevent LINE-1 retrotransposition and the mechanisms of APOBEC3-mediated LINE-1 inhibition has no...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Feng, Yuqing, Goubran, Mariam H., Follack, Tyson B., Chelico, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589869/
https://ncbi.nlm.nih.gov/pubmed/28883657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11344-4
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