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Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells

Replacement of lost beta cells in patients with diabetes has the potential to alleviate them of their disease, yet current protocols to make beta cells are inadequate for therapy. In vitro screens can reveal the signals necessary for endocrine maturation to improve beta cell production, however the...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Scavuzzo, Marissa A., Yang, Diane, Borowiak, Malgorzata
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589819/
https://ncbi.nlm.nih.gov/pubmed/28883507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11169-1
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