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Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells

Replacement of lost beta cells in patients with diabetes has the potential to alleviate them of their disease, yet current protocols to make beta cells are inadequate for therapy. In vitro screens can reveal the signals necessary for endocrine maturation to improve beta cell production, however the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Scavuzzo, Marissa A., Yang, Diane, Borowiak, Malgorzata
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589819/
https://ncbi.nlm.nih.gov/pubmed/28883507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11169-1
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