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Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells

Replacement of lost beta cells in patients with diabetes has the potential to alleviate them of their disease, yet current protocols to make beta cells are inadequate for therapy. In vitro screens can reveal the signals necessary for endocrine maturation to improve beta cell production, however the...

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Publicado en:Sci Rep
Autores principales: Scavuzzo, Marissa A., Yang, Diane, Borowiak, Malgorzata
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589819/
https://ncbi.nlm.nih.gov/pubmed/28883507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11169-1
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