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Tertiary and quaternary structural basis of oxygen affinity in human hemoglobin as revealed by multiscale simulations
Human hemoglobin (Hb) is a benchmark protein of structural biology that shaped our view of allosterism over 60 years ago, with the introduction of the MWC model based on Perutz structures of the oxy(R) and deoxy(T) states and the more recent Tertiary Two-State model that proposed the existence of in...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589765/ https://ncbi.nlm.nih.gov/pubmed/28883619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11259-0 |
| Oznake: |
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