Low body surface area predicts hepatotoxicity of nintedanib in patients with idiopathic pulmonary fibrosis

After the commercialization of nintedanib in Japan, a high incidence of hepatotoxicity resulting in treatment interruption was noted in idiopathic pulmonary fibrosis (IPF) patients treated with nintedanib in our hospital. This study aimed to clarify the risk factors for hepatotoxicity of nintedanib....

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ikeda, Satoshi, Sekine, Akimasa, Baba, Tomohisa, Yamanaka, Yumie, Sadoyama, Shinko, Yamakawa, Hideaki, Oda, Tsuneyuki, Okuda, Ryo, Kitamura, Hideya, Okudela, Koji, Iwasawa, Tae, Ohashi, Kenichi, Takemura, Tamiko, Ogura, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589740/
https://ncbi.nlm.nih.gov/pubmed/28883482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11321-x
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