Mitochondria sustain store-operated currents in colon cancer cells but not in normal colonic cells: reversal by non-steroidal anti-inflammatory drugs

Tumor cells undergo a critical remodeling of intracellular Ca(2+) homeostasis that contribute to important cancer hallmarks. Store-operated Ca(2+) entry (SOCE), a Ca(2+) entry pathway modulated by mitochondria, is dramatically enhanced in colon cancer cells. In addition, most cancer cells display th...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Hernández-Morales, Miriam, Sobradillo, Diego, Valero, Ruth A., Muñoz, Eva, Ubierna, Daniel, Moyer, Mary P., Núñez, Lucía, Villalobos, Carlos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589662/
https://ncbi.nlm.nih.gov/pubmed/28903423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19430
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