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A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome
Lynch syndrome (LS) is one of the most common familial forms of colorectal cancer predisposing syndrome with an autosomal dominant mode of inheritance. LS is caused by the germline mutations in DNA mismatch repair (MMR) genes including MSH2, MLH1, MSH6 and PMS2. Clinically, LS is characterized by hi...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589652/ https://ncbi.nlm.nih.gov/pubmed/28903413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19234 |
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