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A novel heterozygous germline deletion in MSH2 gene in a five generation Chinese family with Lynch syndrome

Lynch syndrome (LS) is one of the most common familial forms of colorectal cancer predisposing syndrome with an autosomal dominant mode of inheritance. LS is caused by the germline mutations in DNA mismatch repair (MMR) genes including MSH2, MLH1, MSH6 and PMS2. Clinically, LS is characterized by hi...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Wu, Bin, Ji, Wuyang, Liang, Shengran, Ling, Chao, You, Yan, Xu, Lai, Zhong, Min-Er, Xiao, Yi, Qiu, Hui-Zhong, Lu, Jun-Yang, Banerjee, Santasree
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589652/
https://ncbi.nlm.nih.gov/pubmed/28903413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19234
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