Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK

Circadian rhythms are regulated by transcriptional and post-translational feedback loops generated by appropriate functions of clock proteins. Rhythmic degradation of the circadian clock proteins is critical for maintenance of the circadian oscillations. Notably, circadian clock does not work during...

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Pubblicato in:Oncotarget
Autori principali: Lu, Yilu, Zheng, Xulei, Hu, Wei, Bian, Shasha, Zhang, Zhiwei, Tao, Dachang, Liu, Yunqiang, Ma, Yongxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589630/
https://ncbi.nlm.nih.gov/pubmed/28903391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18973
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