Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer

Autophagy is a lysosomal degradation and recycling process implicated in cancer progression and therapy resistance. We assessed the impact of basal autophagy in colon cancer (CC) in vitro and ex vivo. Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent incre...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Niklaus, Monique, Adams, Olivia, Berezowska, Sabina, Zlobec, Inti, Graber, Franziska, Slotta-Huspenina, Julia, Nitsche, Ulrich, Rosenberg, Robert, Tschan, Mario P., Langer, Rupert
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589607/
https://ncbi.nlm.nih.gov/pubmed/28903368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17554
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