Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer

Autophagy is a lysosomal degradation and recycling process implicated in cancer progression and therapy resistance. We assessed the impact of basal autophagy in colon cancer (CC) in vitro and ex vivo. Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent incre...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Niklaus, Monique, Adams, Olivia, Berezowska, Sabina, Zlobec, Inti, Graber, Franziska, Slotta-Huspenina, Julia, Nitsche, Ulrich, Rosenberg, Robert, Tschan, Mario P., Langer, Rupert
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589607/
https://ncbi.nlm.nih.gov/pubmed/28903368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17554
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