Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer

Autophagy is a lysosomal degradation and recycling process implicated in cancer progression and therapy resistance. We assessed the impact of basal autophagy in colon cancer (CC) in vitro and ex vivo. Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent incre...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Niklaus, Monique, Adams, Olivia, Berezowska, Sabina, Zlobec, Inti, Graber, Franziska, Slotta-Huspenina, Julia, Nitsche, Ulrich, Rosenberg, Robert, Tschan, Mario P., Langer, Rupert
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589607/
https://ncbi.nlm.nih.gov/pubmed/28903368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17554
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