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The PWWP domain of the human oncogene WHSC1L1/NSD3 induces a metabolic shift toward fermentation
WHSC1L1/NSD3, one of the most aggressive human oncogenes, has two isoforms derived from alternative splicing. Overexpression of long or short NSD3 is capable of transforming a healthy into a cancer cell. NSD3s, the short isoform, contains only a PWWP domain, a histone methyl-lysine reader involved i...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589563/ https://ncbi.nlm.nih.gov/pubmed/28903324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11253 |
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