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Optical Control of Cell Signaling by Single-chain Photoswitchable Kinases
Protein kinases transduce signals to regulate a wide array of cellular functions in eukaryotes. A generalizable method for optical control of kinases would enable fine spatiotemporal interrogation or manipulation of these various functions. Here, we report the design and application of single-chain...
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| Publicado no: | Science |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589340/ https://ncbi.nlm.nih.gov/pubmed/28232577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah3605 |
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