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Optical Control of Cell Signaling by Single-chain Photoswitchable Kinases
Protein kinases transduce signals to regulate a wide array of cellular functions in eukaryotes. A generalizable method for optical control of kinases would enable fine spatiotemporal interrogation or manipulation of these various functions. Here, we report the design and application of single-chain...
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| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589340/ https://ncbi.nlm.nih.gov/pubmed/28232577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah3605 |
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