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Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

A complete, 52-protein, 2.5 million Dalton, Mediator-RNA polymerase II pre-initiation complex (Med-PIC) was assembled and analyzed by cryo-electron microscopy and by chemical cross-linking and mass spectrometry. The resulting complete Med-PIC structure reveals two components of functional significan...

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發表在:Cell
Main Authors: Robinson, Philip J., Trnka, Michael J., Bushnell, David A., Davis, Ralph, Mattei, Pierre-Jean, Burlingame, Alma L., Kornberg, Roger D.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589196/
https://ncbi.nlm.nih.gov/pubmed/27610567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.050
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