In-vivo biological activity and glycosylation analysis of a biosimilar recombinant human follicle-stimulating hormone product (Bemfola) compared with its reference medicinal product (GONAL-f)

Recombinant human follicle-stimulating hormone (r-hFSH) is widely used in fertility treatment. Although biosimilar versions of r-hFSH (follitropin alfa) are currently on the market, given their structural complexity and manufacturing process, it is important to thoroughly evaluate them in comparison...

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發表在:PLoS One
Main Authors: Mastrangeli, Renato, Satwekar, Abhijeet, Cutillo, Francesca, Ciampolillo, Cinzia, Palinsky, Wolf, Longobardi, Salvatore
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589168/
https://ncbi.nlm.nih.gov/pubmed/28880909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184139
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