Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease

Alterations in microRNA (miRNA) expression may contribute to COPD pathogenesis. In COPD, lung fibroblast repair functions are altered in multiple ways, including extracellular mediator release. Our prior study revealed miR-503 expression is decreased in COPD lung fibroblasts, although the exact role...

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Bibliographic Details
Published in:PLoS One
Main Authors: Ikari, Jun, Nelson, Amy J., Obaid, Jannah, Giron-Martinez, Alvaro, Ikari, Kumiko, Makino, Fumihiko, Iwasawa, Shunichiro, Gunji, Yoko, Farid, Maha, Wang, Xingqi, Basma, Hesham, Demeo, Dawn, Feghali-Bostwick, Carol, Holz, Olaf, Rabe, Klaus, Liu, Xiangde, Rennard, Stephen I.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589164/
https://ncbi.nlm.nih.gov/pubmed/28880936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184039
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