Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease

Alterations in microRNA (miRNA) expression may contribute to COPD pathogenesis. In COPD, lung fibroblast repair functions are altered in multiple ways, including extracellular mediator release. Our prior study revealed miR-503 expression is decreased in COPD lung fibroblasts, although the exact role...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ikari, Jun, Nelson, Amy J., Obaid, Jannah, Giron-Martinez, Alvaro, Ikari, Kumiko, Makino, Fumihiko, Iwasawa, Shunichiro, Gunji, Yoko, Farid, Maha, Wang, Xingqi, Basma, Hesham, Demeo, Dawn, Feghali-Bostwick, Carol, Holz, Olaf, Rabe, Klaus, Liu, Xiangde, Rennard, Stephen I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589164/
https://ncbi.nlm.nih.gov/pubmed/28880936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184039
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