RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection

Influenza A virus infection causes substantial morbidity and mortality in seasonal epidemic outbreaks, and more efficient treatments are urgently needed. Innate immune sensing of viral nucleic acids stimulates antiviral immunity, including cell-autonomous antiviral defense mechanisms that restrict v...

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Publicat a:Mol Ther
Autors principals: Coch, Christoph, Stümpel, Jan Phillip, Lilien-Waldau, Vanessa, Wohlleber, Dirk, Kümmerer, Beate M., Bekeredjian-Ding, Isabelle, Kochs, Georg, Garbi, Natalio, Herberhold, Stephan, Schuberth-Wagner, Christine, Ludwig, Janos, Barchet, Winfried, Schlee, Martin, Hoerauf, Achim, Bootz, Friedrich, Staeheli, Peter, Hartmann, Gunther, Hartmann, Evelyn
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589155/
https://ncbi.nlm.nih.gov/pubmed/28760668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.07.003
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