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Reduced FAK-STAT3 signaling contributes to ER stress-induced mitochondrial dysfunction and death in endothelial cells

Excessive endoplasmic reticulum (ER) stress leads to cell loss in many diseases, e.g., contributing to endothelial cell loss after spinal cord injury. Here, we determined whether ER stress-induced mitochondrial dysfunction could be explained by interruption of the focal adhesion kinase (FAK)-mitocho...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Banerjee, Kalpita, Keasey, Matt P., Razskazovskiy, Vladislav, Visavadiya, Nishant P., Jia, Cuihong, Hagg, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589129/
https://ncbi.nlm.nih.gov/pubmed/28495589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.05.007
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