Threshold effect of G9a/Glp on peripheral nerve injury-induced hypersensitivity

BACKGROUND: Previous studies disclosed the pivotal role of methyltransferase complex G9a/Glp in the pathogenesis of neuropathic hypersensitivity induced by peripheral nerve injury. We observed that higher dose of G9a inhibitor improved nociceptive behavior, but the lower dose worsened pain. The aim...

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Udgivet i:Mol Pain
Main Authors: Wang, Xian, Shen, Xiaofeng, Ma, Shaolei, Liu, Yusheng, Xu, Shiqin, Wu, Shizheng, Wang, Fuzhou
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588794/
https://ncbi.nlm.nih.gov/pubmed/28814147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917729305
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